非小细胞肺癌顺铂化疗耐药相关miRNA的筛选鉴定.pdfVIP

广州医学院硕士研究生论文 非小细胞肺癌顺铂化疗耐药相关 miRNA 的筛选、鉴定 Screening and identification of miRNA associated with DDP resistance in non-small cell lung cancer ABSTRACT Chemotherapy is an important therapeutic approach for the therapy of advanced NSCLC cancer, but a successful long-term treatment is prevented by the development of drug resistance. Recent works have underlined the involvement of non-coding RNAs,MicroRNAs (miRNAs)are a small noncoding family of～22 nt RNAs that play an important