A novel autoantibody against fibronectin leucine-rich transmembrane protein 2 expressed on the endothelial cell surface identified by retroviral vector system in systemic lupus erythematosus.docVIP

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2017-05-15 发布于上海
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A novel autoantibody against fibronectin leucine-rich transmembrane protein 2 expressed on the endothelial cell surface identified by retroviral vector system in systemic lupus erythematosus.doc

A novel autoantibody against fibronectin leucine-rich transmembrane protein 2 expressed on the endothelial cell surface identified by retroviral vector system in systemic lupus erythematosus

Shiraietal.ArthritisResearchTherapy2012,14:R157 /content/14/4/R157 RESEARCH ARTICLE OpenAccess Anovelautoantibodyagainstfibronectinleucine- richtransmembraneprotein2expressedonthe endothelialcellsurfaceidentifiedbyretroviral vectorsysteminsystemiclupuserythematosus TsuyoshiShirai1,HiroshiFujii1*,MasaoOno2,KyoheiNakamura1,RyuWatanabe1,YumiTajima1, NaruhikoTakasawa1,TomonoriIshii1andHideoHarigae1 Abstract Introduction:Anti-endothelialcellantibodies(AECAs)arethoughttobecriticalforvasculitidesincollagen diseases,butmostweredirectedagainstmoleculeslocalizedwithinthecellandnotexpressedonthecellsu

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A novel autoantibody against fibronectin leucine-rich transmembrane protein 2 expressed on the endothelial cell surface identified by retroviral vector system in systemic lupus erythematosus.docVIP