原创力文档A novel method to quantify IRDye800CW fluorescent antibody probes ex vivo in tissue distribution studies.docVIP
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A novel method to quantify IRDye800CW fluorescent antibody probes ex vivo in tissue distribution studies
Oliveiraetal.EJNMMIResearch2012,2:50
/content/2/1/50
ORIGINAL RESEARCH
OpenAccess
AnovelmethodtoquantifyIRDye800CW
fluorescentantibodyprobesexvivointissue
distributionstudies
SabrinaOliveira1,2,RuthCohen3,MarijkeStigter-vanWalsum3,GuusAMSvanDongen3,SjoerdGElias4,
PaulJvanDiest2,WillemMali5andPaulMPvanBergenenHenegouwen1*
Abstract
Background:WedescribeanewmethodforbiodistributionstudieswithIRDye800CWfluorescentantibodyprobes.
ThismethodallowsthequantificationoftheIRDye800CWfluorescenttracerinpercentageofinjecteddoseper
gramoftissue(%ID/g),anditishereincomparedtothegenerallyusedreferencemetho
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