A novel, rapidly acquired and persistent spatial memory task that induces immediate early gene expression.docVIP

Feldman et al. Behavioral and Brain Functions 2010, 6:35 /content/6/1/35 METHODOLOGY Open Access A novel, rapidly acquired and persistent spatial Methodology memory task that induces immediate early gene expression Lisa A Feldman1, Matthew L Shapiro2 and Josephine Nalbantoglu*1 Abstract Background: The Morris water maze task is a hippocampus-dependent learning and memory test that typically takes between 3 days to 2 weeks of training. This task is used to assess spatial learning and induces the expression of genes known to be crucial to learning and memory in the hippocampus. A major cave