原创力文档A randomized controlled trial of isotonic versus hypotonic maintenance intravenous fluids in hospitalized children.docVIP
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A randomized controlled trial of isotonic versus hypotonic maintenance intravenous fluids in hospitalized children
Sabaetal.BMCPediatrics2011,11:82
/1471-2431/11/82
RESEARCH ARTICLE
OpenAccess
Arandomizedcontrolledtrialofisotonicversus
hypotonicmaintenanceintravenousfluidsin
hospitalizedchildren
ThomasGSaba1,JamesFairbairn2,FionaHoughton1,DianeLaforte1andBethanyJFoster1,3*
Abstract
Background:Isotonicsalinehasbeenproposedasasaferalternativetotraditionalhypotonicsolutionsfor
intravenous(IV)maintenancefluidstopreventhyponatremia.However,theoptimaltonicityofmaintenance
intravenousfluidsinhospitalizedchildrenhasnotbeendetermined.Theobjectiveofthisstudywastoestimate
andcomparetheratesofchangeinserumsodium([N
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