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A sampling algorithm for segregation analysis
Genet. Sel. Evol. 33(2001) 587–603
?INRA, EDP Sciences, 2001
587
Original article
Asamplingalgorithmforsegregation
analysis
BruceTIER?,JohnHENSHALL
AnimalGeneticsandBreedingUnit??,UniversityofNewEngland,
ArmidaleNSW2351,Australia
(Received27June2000;accepted12June2001)
Abstract– MethodsfordetectingQuantitativeTraitLoci(QTL)withoutmarkershavegenerally
usediterativepeelingalgorithmsfordetermininggenotypeprobabilities.Thesealgorithmshave
considerable shortcomings in complex pedigrees. A Monte Carlo Markov chain (MCMC)
methodwhichsamplesthepedigreeofthewholepopulationjointlyisdescribed. Simu
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