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A sampling algorithm for segregation analysis

Genet. Sel. Evol. 33(2001) 587–603 ?INRA, EDP Sciences, 2001 587 Original article Asamplingalgorithmforsegregation analysis BruceTIER?,JohnHENSHALL AnimalGeneticsandBreedingUnit??,UniversityofNewEngland, ArmidaleNSW2351,Australia (Received27June2000;accepted12June2001) Abstract– MethodsfordetectingQuantitativeTraitLoci(QTL)withoutmarkershavegenerally usediterativepeelingalgorithmsfordetermininggenotypeprobabilities.Thesealgorithmshave considerable shortcomings in complex pedigrees. A Monte Carlo Markov chain (MCMC) methodwhichsamplesthepedigreeofthewholepopulationjointlyisdescribed. Simu

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