A simpler method of preprocessing MALDI-TOF MS data for differential biomarker analysis stem cell and melanoma cancer studies.docVIP
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A simpler method of preprocessing MALDI-TOF MS data for differential biomarker analysis stem cell and melanoma cancer studies
Tongetal.ClinicalProteomics2011,8:14
/content/8/1/14
CLINICAL
PROTEOMICS
RESEARCH
OpenAccess
AsimplermethodofpreprocessingMALDI-TOF
MSdatafordifferentialbiomarkeranalysis:stem
cellandmelanomacancerstudies
DongLTong1*,DavidJBoocock1,ClareCoveney1,JaimySaif1,SusanaGGomez2,SergioQuerol2,RobertRees1
andGrahamRBall1
*Correspondence:dong.tong@ntu.
Abstract
ac.uk
1TheJohnvanGeestCancer
ResearchCentre,SchoolofScience
andTechnology,NottinghamTrent
Introduction:Rawspectraldatafrommatrix-assistedlaserdesorption/ionisation
time-of-flight(MALDI-TOF)withMSprofilingtechniquesusuallycontainscomplex
Universi
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