Acid-Sensing Ion Channels and Pain.docVIP

Pharmaceuticals 2010, 3, 1411-1425; doi:10.3390/ph3051411 OPEN ACCESS pharmaceuticals ISSN 1424-8247 /journal/pharmaceuticals Review Acid-Sensing Ion Channels and Pain Qihai Gu * and Lu-Yuan Lee Department of Physiology, University of Kentucky Medical Center, 800 Rose Street, Lexington, KY 40536-0298, USA; E-Mails: lylee@ (L.Y.L.) * Author to whom correspondence should be addressed; E-Mail: qgu2@ Tel.: +1-859-323-5348; Fax: +1-859-323-1070. Received: 02 April 2010; in revised form: 14 April 2010 / Accepted: 07 May 2010 / Published: 11 May 2010 Abstract: Pathophysiological conditions such