Acquisition of rifabutin resistance by a rifampicin resistant mutant of Mycobacterium tuberculosis involves an unusual spectrum of mutations and elevated frequency.docVIP

Annals of Clinical Microbiology and Antimicrobials BioMedCentral Research Open Access Acquisition of rifabutin resistance by a rifampicin resistant mutant of Mycobacterium tuberculosis involves an unusual spectrum of mutations and elevated frequency Richard M Anthony*1, Anja RJ Schuitema1, Indra L Bergval1, Tim J Brown2, Linda Oskam1 and Paul R Klatser1 Address: 1KIT (Royal Tropical Institute) Biomedical Research, Meibergdreef 39, 1105 AZ Amsterdam, The Netherlands and 2Health Protection Agency, Mycobacterium Reference Unit, Kings College Hospital (Dulwich), London, UK Email: Richard M