An evaluation of ciprofloxacin pharmacokinetics in critically ill patients undergoing continuous veno-venous haemodiafiltration.docVIP

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An evaluation of ciprofloxacin pharmacokinetics in critically ill patients undergoing continuous veno-venous haemodiafiltration.doc

An evaluation of ciprofloxacin pharmacokinetics in critically ill patients undergoing continuous veno-venous haemodiafiltration

Spooneretal.BMCClinicalPharmacology2011,11:11 /1472-6904/11/11 RESEARCH ARTICLE OpenAccess Anevaluationofciprofloxacinpharmacokinetics incriticallyillpatientsundergoingcontinuous veno-venoushaemodiafiltration AlmathMSpooner1,CatherineDeegan2,DeirdreMD’Arcy1,CaitrionaMGowing3,MariaBDonnelly2*and OwenICorrigan1 Abstract Background:Thestudyaimedtoinvestigatethepharmacokineticsofintravenousciprofloxacinandtheadequacy of400mgevery12hoursincriticallyillIntensiveCareUnit(ICU)patientsoncontinuousveno-venous haemodiafiltration(CVVHDF)withparticularreferencetotheeffectofachievedflowratesondrugclearan

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An evaluation of ciprofloxacin pharmacokinetics in critically ill patients undergoing continuous veno-venous haemodiafiltration.docVIP