An increased incidence of Hodgkins lymphoma in patients with adult-onset sarcoma.docVIP

Downingetal.ClinicalSarcomaResearch2012,2:1 /content/2/1/1 CLINICAL SARCOMA RESEARCH RESEARCH OpenAccess AnincreasedincidenceofHodgkin’ slymphoma inpatientswithadult-onsetsarcoma MeganEDowning1,2,GillianSDite3andMandyLBallinger2* ,for TheInternationalSarcomaKindredStudyConsortium2 Abstract Background:Sarcomasarerare,oftenfatalmalignanciesofconnectivetissuesthatcanoccuringeneticpredisposition syndromesorresultfromcarcinogenexposure.Hodgkin’slymphoma(HL)isnotknowntocontributetoanyrecognised familialcancersyndromecomprisingsarcomas,butisknowntobeassociatedwithavarietyofsecondcancers, includings