原创力文档Association of COMT Val158Met polymorphism and breast cancer risk an updated meta-analysis.docVIP
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Association of COMT Val158Met polymorphism and breast cancer risk an updated meta-analysis
Qinetal.DiagnosticPathology2012,7:136
/content/7/1/136
RESEARCH
OpenAccess
AssociationofCOMTVal158Metpolymorphism
andbreastcancerrisk:anupdatedmeta-analysis
XueQin1?,QiliuPeng1,5?,AipingQin2?,ZhipingChen3?,LiwenLin1,YanDeng1,LiXie1,JuanjuanXu1,HaiweiLi1,
TaijieLi1,ShanLi1*andJinminZhao4*
Abstract
Background:Catechol-O-methyltransferase(COMT)isoneofthemostimportantenzymesinvolvedinestrogen
metabolismanditsfunctionalgeneticpolymorphismsmaybeassociatedwithbreastcancer(BC)risk.Many
epidemiologicalstudieshavebeenconductedtoexploretheassociationbetweentheCOMTVal158Met
polymorphismandbreastcancerri
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