原创力文档Association of cytokine and matrix metalloproteinase profiles with disease activity and function in ankylosing spondylitis.docVIP
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Association of cytokine and matrix metalloproteinase profiles with disease activity and function in ankylosing spondylitis
Matteyetal.ArthritisResearchTherapy2012,14:R127
/content/14/3/R127
RESEARCH ARTICLE
OpenAccess
Associationofcytokineandmatrix
metalloproteinaseprofileswithdiseaseactivity
andfunctioninankylosingspondylitis
DerekLMattey1,2*,JonathanCPackham1,NicolaBNixon1,LucyCoates3,PaulCreamer4,SarahHailwood5,
GordonJTaylor3andAshokKBhalla3
Abstract
Introduction:Thepathologyofankylosingspondylitis(AS)suggeststhatcertaincytokinesandmatrix
metalloproteinases(MMPs)mightprovideusefulmarkersofdiseaseactivity.Serumlevelsofsomecytokinesand
MMPshavebeenfoundtobeelevatedinactivedisease,butthereisagenerallackofinfor
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