Automatic Supported Liquid Extraction (SLE) Coupled with HILIC-MSMS An Application to Method Development and Validation of Erlotinib in Human Plasma.docVIP

Pharmaceutics 2010, 2, 105–118; doi:10.3390/pharmaceutics2020105 OPEN ACCESS pharmaceutics ISSN 1999-4923 /journal/pharmaceutics Article Automatic Supported Liquid Extraction (SLE) Coupled with HILIC-MS/MS: An Application to Method Development and Validation of Erlotinib in Human Plasma Jiongwei Pan 1,*, Xiangyu Jiang 2 and Yu-Luan Chen 3 1 Charles River Laboratories, 334 South Street, Shrewsbury, MA 01545, USA 2 Covance Laboratories, 3301 Kinsman Boulevard, Madison, WI 53704, USA; E-Mail: xiangyu.jiang@ (X.J.) 3 Sepracor Inc., 84 Waterford Drive, Marlborough, MA 01752, USA; E-Mail: yu-lua