B cells in rheumatoid arthritis.docVIP

/content/2/2/126 Review Bcells in rheumatoid arthritis Hye-Jung Kim and Claudia Berek Deutsches Rheuma ForschungsZentrum, Berlin, Germany Received: 21 January 2000 Arthritis Res 2000,2:126–131 Revisions requested: 2 February 2000 Revisions received: 3 February 2000 Accepted: 7 February 2000 The electronic version of this article can be found online at /content/2/2/126 Published: 24 February 2000 ? Current Science Ltd Abstract Normally the immune response is restricted to the peripheral secondary lymphoid organs. However, additional ectopic lymphoid tissue may develop at chronic sites of