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- 2017-05-15 发布于上海
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B lymphocyte-typing for prediction of clinical response to rituximab
Brezinscheketal.ArthritisResearchTherapy2012,14:R161
/content/14/4/R161
RESEARCH ARTICLE
OpenAccess
Blymphocyte-typingforpredictionofclinical
responsetorituximab
Hans-PeterBrezinschek1*,FranzRainer2,KerstinBrickmann1andWinfriedBGraninger1
Abstract
Introduction:Thepredictionoftherapeuticresponsetorituximabinrheumatoidarthritisisdesirable.We
evaluatedwhetheranalysisofBlymphocytesubsetsbyflowcytometrywouldbeusefultoidentifynon-responders
torituximabaheadoftime.
Methods:Fifty-twopatientswithactiverheumatoidarthritisdespitetherapywithTNF-inhibitorswereincludedin
thenationalrituximabregistry.DAS2
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