原创力文档Bimodal action of the flavonoid quercetin on basophil function an investigation of the putative biochemical targets.docVIP
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Bimodal action of the flavonoid quercetin on basophil function an investigation of the putative biochemical targets
Chirumboloetal.ClinicalandMolecularAllergy2010,8:13
/content/8/1/13
CMA
RESEARCH
OpenAccess
Bimodalactionoftheflavonoidquercetinon
basophilfunction:aninvestigationofthe
putativebiochemicaltargets
SalvatoreChirumbolo1*,MartaMarzotto1,AnitaConforti2,AntonioVella3,RiccardoOrtolani3,PaoloBellavite1
Abstract
Background:Flavonoids,alargegroupofpolyphenolicmetabolitesderivedfromplantshavereceivedagreatdeal
ofattentionoverthelastseveraldecadesfortheirpropertiesininflammationandallergy.Quercetin,themost
abundantofplantflavonoids,exertsamodulatoryactionatnanomolarconcentrationsonhumanbasophils.Asthis
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