Binding of TS1, an anti-keratin 8 antibody, in small-cell lung cancer after 177Lu-DOTA-Tyr3-octreotate treatment a histological study in xenografted mice.docVIP

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Binding of TS1, an anti-keratin 8 antibody, in small-cell lung cancer after 177Lu-DOTA-Tyr3-octreotate treatment a histological study in xenografted mice.doc

Binding of TS1, an anti-keratin 8 antibody, in small-cell lung cancer after 177Lu-DOTA-Tyr3-octreotate treatment a histological study in xenografted mice

Erlandssonetal.EJNMMIResearch2011,1:19 /content/1/1/19 ORIGINAL RESEARCH OpenAccess BindingofTS1,ananti-keratin8antibody,in 177 3 small-celllungcancerafter Lu-DOTA-Tyr - octreotatetreatment:ahistologicalstudyin xenograftedmice AnnErlandsson1*,EvaForssell-Aronsson2,TomasSeidal1andPeterBernhardt2 Abstract Background:Small-celllungcarcinoma(SCLC)isanaggressivemalignancycharacterisedbyanearlyrelapse,a tendencytowardsdrugresistance,andahighincidenceofmetastasis.SCLCcellsareofneuroendocrineoriginand expresshighlevelsofsomatostatinreceptors;therefore,futuretreatmentmightinvolvetargetingtumoursw

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Binding of TS1, an anti-keratin 8 antibody, in small-cell lung cancer after 177Lu-DOTA-Tyr3-octreotate treatment a histological study in xenografted mice.docVIP