原创力文档Bone events and evolution of biologic markers in Gaucher disease before and during treatment.docVIP
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Bone events and evolution of biologic markers in Gaucher disease before and during treatment
Stirnemannetal.ArthritisResearchTherapy2010,12:R156
/content/12/4/R156
RESEARCH ARTICLE
OpenAccess
Boneeventsandevolutionofbiologicmarkersin
Gaucherdiseasebeforeandduringtreatment
Jér?meStirnemann1,2*,NadiaBelmatoug3,CorineVincent2,OlivierFain1,BrunoFantin3,FranceMentré2
Abstract
Introduction:KnownbiomarkersofGaucher-diseaseactivityareplatelets,chitotriosidase,angiotensin-converting
enzyme(ACE),tartrate-resistantacidphosphatase(TRAP)andferritin.Theaimofthisstudywastoretrospectively
evaluatethefrequencyofboneevents(BE)andbiomarkerchangesduringtwoperiods:diagnosistofirstenzyme-
replacementthe
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