Boswellic acids extract attenuates pulmonary fibrosis induced by bleomycin and oxidative stress from gamma irradiation in rats.docVIP
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Boswellic acids extract attenuates pulmonary fibrosis induced by bleomycin and oxidative stress from gamma irradiation in rats
AliandMansourChineseMedicine2011,6:36
/content/6/1/36
RESEARCH
OpenAccess
Boswellicacidsextractattenuatespulmonary
fibrosisinducedbybleomycinandoxidative
stressfromgammairradiationinrats
EmanNoamanAliandSomayaZakariaMansour*
Abstract
Background:Interstitialpulmonaryfibrosisischaracterizedbyanalteredcellularcompositionofthealveolar
regionwithexcessivedepositionofcollagen.Lunginflammationisalsocommoninpulmonaryfibrosis.Thisstudy
aimstotesttheinhibitionof5-lipooxygenase(5-LOX)byboswellicacid(BA)extractinanexperimentalmodelof
pulmonaryfibrosisusingbleomycin(BL).
Methods:Boswellicacidextract(1g/k
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