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Campylobacter jejuni induces transcytosis of commensal bacteria across the intestinal epithelium through M-like cells.docVIP

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Campylobacter jejuni induces transcytosis of commensal bacteria across the intestinal epithelium through M-like cells.doc

    Campylobacter jejuni induces transcytosis of commensal bacteria across the intestinal epithelium through M-like cells

    Kalischuketal.GutPathogens2010,2:14 /content/2/1/14 RESEARCH OpenAccess Campylobacterjejuniinducestranscytosisof commensalbacteriaacrosstheintestinal epitheliumthroughM-likecells LisaDKalischuk,FrancesLeggett,GDouglasInglis* Abstract Background:RecentepidemiologicalanalyseshaveimplicatedacuteCampylobacterenteritisasafactorthatmay inciteorexacerbateinflammatoryboweldisease(IBD)insusceptibleindividuals.Wehavedemonstratedpreviously thatC.jejunidisruptstheintestinalbarrierfunctionbyrapidlyinducingepithelialtranslocationofnon-invasive commensalbacteriaviaatranscellularlipidraft-mediatedmechanism(

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