Change in Hemoglobin Levels due to Anesthesia in Mice An Important Confounder in Studies on Hematopoietic Drugs.docVIP

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Change in Hemoglobin Levels due to Anesthesia in Mice An Important Confounder in Studies on Hematopoietic Drugs.doc

Change in Hemoglobin Levels due to Anesthesia in Mice An Important Confounder in Studies on Hematopoietic Drugs

ChangeinHemoglobinLevelsduetoAnesthesiainMice: AnImportantConfounderinStudiesonHematopoieticDrugs AnitaGothelf,PernilleHojman,andJulieGehl Abstract Analgesicandanestheticdrugsmayhaveanimpactontheresultsachievedfromanimalexperiments.In thestudypresentedhere,wetrytoenlightenwhetheranesthesiawithfentanyl/fluniasoneandmidazolam (HypnormandDormicum) hasaninfluence onmeasurements ofhemoglobin inmice.Inacross-over study,wehavecomparedhemoglobinlevelsintwogroupsofmice:anesthetizedversusnon-anesthetized and found significant decrease in hemoglobin levels in the anesthetized group (pG0.05) unrelated

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