Chlamydia trachomatis growth inhibition and restoration of LDL-receptor level in HepG2 cells treated with mevastatin.docVIP

Bashmakovetal.ComparativeHepatology2010,9:3 /content/9/1/3 RESEARCH OpenAccess Chlamydiatrachomatisgrowthinhibitionand restorationofLDL-receptorlevelinHepG2cells treatedwithmevastatin YuriyKBashmakov1*?,NailyaAZigangirova1,2?,YuliaPPashko2,LidiaNKapotina2,IvanMPetyaev1 Abstract Background:PerihepatitisisrarebutconsistentlyoccurringextragenitalmanifestationofuntreatedChlamydia trachomatisinfection.DespiteofpossibleliverinvolvementingeneralizedC.trachomatisinfection,theabilityofthe pathogentopropagateinthehepaticcellsanditsimpactonliverfunctionsisnotthoroughlyinvestigated.The effectofmevastati