Chondroprotective effects and mechanisms of resveratrol in advanced glycation end products-stimulated chondrocytes.docVIP
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Chondroprotective effects and mechanisms of resveratrol in advanced glycation end products-stimulated chondrocytes
Liuetal.ArthritisResearchTherapy2010,12:R167
/content/12/5/R167
RESEARCH ARTICLE
OpenAccess
Chondroprotectiveeffectsandmechanismsof
resveratrolinadvancedglycationendproducts-
stimulatedchondrocytes
Feng-ChengLiu1,2,Li-FengHung3,Wan-LinWu3,Deh-MingChang1,2,Chuan-YuehHuang3,Jenn-HaungLai1,2*,
Ling-JunHo3,4*
Abstract
Introduction:Accumulationofadvancedglycationendproducts(AGEs)injointscontributestothepathogenesis
ofcartilagedamageinosteoarthritis(OA).Weaimtoexplorethepotentialchondroprotectiveeffectsofresveratrol
onAGEs-stimulatedporcinechondrocytesandcartilageexplants.
Methods:Chondrocyteswer
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