Chronictreatment with Carvedilol improves ventricular function and reducesmyocyte apoptosis in an animal model of heart failure.docVIP

BMC Physiology BioMedCentral Research article Open Access Chronic treatment with Carvedilol improves ventricular function and reduces myocyte apoptosis in an animal model of heart failure Chukwuka C Okafor1,2, Cynthia Perreault-Micale3,5, Roger J Hajjar4, Djamel Lebeche3, Klara Skiroman3, George Jabbour4, Angelia A Doye3, Michael X Lee3,5, Nancy Laste6 and Judith K Gwathmey*1,3,5 Address: 1Boston University Medical Center, Boston, USA, 2Cartilage Biology and Orthopaedics Branch, National Institutes of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda,