Clara cell protein in nasal lavage fluid and nasal nitric oxide - biomarkers with anti-inflammatory properties in allergic rhinitis.docVIP
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Iranderetal.ClinicalandMolecularAllergy2012,10:4
/content/10/1/4
CMA
RESEARCH
OpenAccess
Claracellproteininnasallavagefluidandnasal
nitricoxide-biomarkerswithanti-inflammatory
propertiesinallergicrhinitis
KristinaIrander1,J?rgenPPalm2,MagnusPBorres3,4 andBijarGhafouri5,6*
Abstract
Background:Claracellprotein(CC16)isascribedaprotectiveandanti-inflammatoryroleinairwayinflammation.
Lowerlevelshavebeenobservedinasthmaticsubjectsaswellasinsubjectswithintermittentallergicrhinitisthan
inhealthycontrols.Nasalnitricoxide(nNO)ispresentinhighconcentrationsintheupperairways,andconsidered
abiomarkerwi
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