Citrullinated vimentin as an important antigen in immune complexes from synovial fluid of rheumatoid arthritis patients with antibodies against citrullinated proteins.docVIP

Van Steendam et al. Arthritis Research Therapy 2010, 12:R132 /content/12/4/R132 RESEARCH ARTICLE Open Access Citrullinated vimentin as an important antigen in Research article immune complexes from synovial fluid of rheumatoid arthritis patients with antibodies against citrullinated proteins Katleen Van Steendam1, Kelly Tilleman1, Marlies De Ceuleneer1, Filip De Keyser2, Dirk Elewaut2 and Dieter Deforce*1 Abstract Introduction: Rheumatoid arthritis (RA) is an inflammatory disease, which results in destruction of the joint. The presence of immune complexes (IC) in serum and synovial f