Cis-regulation of IRF5 expression is unable to fully account for systemic lupus erythematosus association analysis of multiple experiments with lymphoblastoid cell lines.docVIP

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2017-05-16 发布于上海
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Cis-regulation of IRF5 expression is unable to fully account for systemic lupus erythematosus association analysis of multiple experiments with lymphoblastoid cell lines.doc

Alonso-Perezetal.ArthritisResearchTherapy2011,13:R80 /content/13/3/R80 RESEARCH ARTICLE OpenAccess Cis-regulationofIRF5expressionisunableto fullyaccountforsystemiclupuserythematosus association:analysisofmultipleexperiments withlymphoblastoidcelllines ElisaAlonso-Perez1?,MarianSuarez-Gestal1?,ManuelCalaza1,TonyKwan2,JacekMajewski2,JuanJGomez-Reino1,3 andAntonioGonzalez1* Abstract Introduction:Interferonregulatoryfactor5gene(IRF5)polymorphismsarestronglyassociatedwithseveraldiseases, includingsystemiclupuserythematosus(SLE).Theassociationincludesriskandprotectivecomponents.Theycouldbe duetoc

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Cis-regulation of IRF5 expression is unable to fully account for systemic lupus erythematosus association analysis of multiple experiments with lymphoblastoid cell lines.docVIP