Circulating soluble urokinase plasminogen activator receptor is stably elevated during the first week of treatment in the intensive care unit and predicts mortality in critically ill patients.docVIP

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Circulating soluble urokinase plasminogen activator receptor is stably elevated during the first week of treatment in the intensive care unit and predicts mortality in critically ill patients.doc

Kochetal.CriticalCare2011,15:R63 /content/15/1/R63 RESEARCH OpenAccess Circulatingsolubleurokinaseplasminogen activatorreceptorisstablyelevatedduringthe firstweekoftreatmentintheintensivecareunit andpredictsmortalityincriticallyillpatients AlexanderKoch1,SebastianVoigt1,CarstenKruschinski2,EdouardSanson1,HannaDückers1,AndreasHorn1, ErayYagmur3,HenningZimmermann1,ChristianTrautwein1andFrankTacke1* Abstract Introduction:suPARisthesolubleformoftheurokinaseplasminogenactivatorreceptor(uPAR),whichis expressedinvariousimmunologicallyactivecells.HighsuPARserumconcentrationsaresuggestedtoreflectthe

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