Circulating retinol binding protein 4 in critically ill patients before specific treatment prognostic impact and correlation with organ function, metabolism and inflammation.docVIP

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Circulating retinol binding protein 4 in critically ill patients before specific treatment prognostic impact and correlation with organ function, metabolism and inflammation.doc

Kochetal.CriticalCare2010,14:R179 /content/14/5/R179 RESEARCH OpenAccess Circulatingretinolbindingprotein4incriticallyill patientsbeforespecifictreatment:prognostic impactandcorrelationwithorganfunction, metabolismandinflammation AlexanderKoch1,RalfWeiskirchen2,EdouardSanson1,HenningWZimmermann1,SebastianVoigt1, HannaDückers1,ChristianTrautwein1,FrankTacke1* Abstract Introduction:Hyperglycemiaandinsulinresistancearewell-knownfeaturesofcriticalillnessandimpactthe mortalityrate,especiallyinsepsis.Retinolbindingprotein4(RBP4)promotesinsulinresistanceinmiceandis systemicallyelevatedinpatientswit

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Circulating retinol binding protein 4 in critically ill patients before specific treatment prognostic impact and correlation with organ function, metabolism and inflammation.docVIP