Clinical Efficacy and Laboratory Improvement of Bacillus Calmette-Guerin Vaccination on Adult Atopic Asthma A Cohort Study.docVIP

ORIGINALARTICLE ClinicalEfficacyandLaboratoryImprovementofBacillus Calmette-GuerinVaccinationonAdultAtopicAsthma ACohortStudy EulisA.Datau,MD,*H.Mewengkang,MD,TJ.C.Matheos,MD,TI.Purnawan,MD,*M.Wibisono,MD,* K.Wongdjaja,MD,*C.Wibowo,MD,*E.Surachmanto,MD,*andF.P.Salim,MD* KeyWords:BCG,symptom/drugscore,IFN-F,IL-4,TGF-A1, Background: Recent studies have shown that Bacillus Calmette- adult,atopy,asthma Guerin (BCG) vaccination is inversely related to asthma, a Th2 cellYassociatedwithallergicdisease,whichBCGinhumansinduces Th1-cellimmuneresponsesandpreventsairwayremodeling. (WAOJournal2008;63Y69)