Clinical Management of Adult Patients with a History of Nonsteroidal Anti-Inflammatory Drug-Induced UrticariaAngioedema Update.docVIP

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Clinical Management of Adult Patients with a History of Nonsteroidal Anti-Inflammatory Drug-Induced UrticariaAngioedema Update.doc

Clinical Management of Adult Patients with a History of Nonsteroidal Anti-Inflammatory Drug-Induced UrticariaAngioedema Update

ORIGINAL ARTICLE ClinicalManagementofAdultPatientswithaHistoryof NonsteroidalAnti-InflammatoryDrug–InducedUrticaria/ Angioedema:Update RiccardoAsero,MD Inthelargemajorityofpreviousstudies,patientswithahistoryofacuteurticariainducedbynonsteroidalanti-inflammatorydrugs (NSAIDs) seeking safe alternative drugs have undergone tolerance tests uniquely with compounds exerting little or no inhibitory effectonthecyclooxygenase1enzyme.Inlightofrecentlypublishedstudies,however,thisapproachseemsinadequateandshould bechanged.Thepresentarticlecriticallyreviewstheclinicalmanagementofpatientspresentingwitha

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Clinical Management of Adult Patients with a History of Nonsteroidal Anti-Inflammatory Drug-Induced UrticariaAngioedema Update.docVIP