Clinical Management of Nonsteroidal Anti-inflammatory Drug Hypersensitivity.docVIP

REVIEWARTICLE ClinicalManagementofNonsteroidalAnti-inflammatory DrugHypersensitivity MarioSa′nchez-Borges,MD CLINICALSPECTRUMANDPATHOGENESIS A wide variety of clinical manifestations can be Abstract: Hypersensitivity diseases caused by nonsteroidal anti- in?ammatoryagentsarerelativelycommoninthepopulation.This produced by NSAIDs. Using the classi?cation proposed by articlesummarizesthepresentunderstandingonthevariousallergic theNomenclatureCommitteeoftheWorldAllergyOrganiza- andnonallergicclinicalpicturesproducedthroughhypersensitivityto 6 tion, thefollowingtypesofhypersensitivityreactionsc