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Clinical significance of antibodies to Ro52TRIM21 in systemic sclerosis
Hudsonetal.ArthritisResearchTherapy2012,14:R50
/content/14/2/R50
RESEARCH ARTICLE
OpenAccess
ClinicalsignificanceofantibodiestoRo52/TRIM21
insystemicsclerosis
MarieHudson1,2*,JanetPope3,MichaelMahler4,SolèneTatibouet2,RussellSteele2andMurrayBaron1,2 ,for
CanadianSclerodermaResearchGroup(CSRG)andMarvinJFritzler5
Abstract
Introduction:AutoantibodiestoRo52recentlyidentifiedasTRIM21areamongthemostcommonautoantibodies
insystemicautoimmunerheumaticdiseases,buttheirclinicalassociationremainspoorlyunderstood.We
undertookthisstudytodeterminetheclinicalandserologicassociationsofanti-Ro52/TRIM21antibo
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