Combinations of physiologic estrogens with xenoestrogens alter calcium and kinase responses, prolactin release, and membrane estrogen receptor trafficking in rat pituitary cells.docVIP

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Combinations of physiologic estrogens with xenoestrogens alter calcium and kinase responses, prolactin release, and membrane estrogen receptor trafficking in rat pituitary cells.doc

Combinations of physiologic estrogens with xenoestrogens alter calcium and kinase responses, prolactin release, and membrane estrogen receptor trafficking in rat pituitary cells

Jengetal.EnvironmentalHealth2010,9:61 /content/9/1/61 RESEARCH OpenAccess Combinationsofphysiologicestrogenswith xenoestrogensaltercalciumandkinase responses,prolactinrelease,andmembrane estrogenreceptortraffickinginratpituitarycells Yow-JiunJeng,MikhailKochukov,CherylSWatson* Abstract Background:XenoestrogenssuchasalkylphenolsandthestructurallyrelatedplasticbyproductbisphenolAhave recentlybeenshowntoactpotentlyvianongenomicsignalingpathwaysandthemembraneversionofestrogen receptor-a.Thoughtheresponsestothesecompoundsaretypicallymeasuredindividually,theyusually contaminateorganismsthatalready

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