原创力文档Colistin recent data on pharmacodynamics properties and clinical efficacy in critically ill patients.docVIP
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- 2017-05-16 发布于上海
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Colistin recent data on pharmacodynamics properties and clinical efficacy in critically ill patients
MichalopoulosandFalagasAnnalsofIntensiveCare2011,1:30
/content/1/1/30
REVIEW
OpenAccess
Colistin:recentdataonpharmacodynamics
propertiesandclinicalefficacyincriticallyill
patients
ArgyrisSMichalopoulos1,2 andMatthewEFalagas2,3,4*
Abstract
Recentclinicalstudiesperformedinalargenumberofpatientsshowedthatcolistin“forgotten”forseveraldecades
revivedforthemanagementofinfectionsduetomultidrug-resistant(MDR)Gram-negativebacteria(GNB)andhad
acceptableeffectivenessandconsiderablylesstoxicitythanthatreportedinolderpublications.Colistinisarapidly
bactericidalantimicrobialagentthatpossessesasignificant
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