原创力文档Combining creatinine and volume kinetics identifies missed cases of acute kidney injury following cardiac arrest.docVIP
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Combining creatinine and volume kinetics identifies missed cases of acute kidney injury following cardiac arrest
Pickeringetal.CriticalCare2013,17:R7
/content/17/1/R7
RESEARCH
OpenAccess
Combiningcreatinineandvolumekinetics
identifiesmissedcasesofacutekidneyinjury
followingcardiacarrest
JohnWPickering1*,AzrinaMdRalib1andZoltánHEndre1,2
Abstract
Introduction:Fluidresuscitationinthecriticallyilloftenresultsinapositivefluidbalance,potentiallydilutingthe
serumcreatinineconcentrationanddelayingdiagnosisofacutekidneyinjury(AKI).
Methods:DilutionduringAKIwasquantifiedbycombiningcreatinineandvolumekineticstoaccountforfluid
type,andratesoffluidinfusionandurineoutput.Themodelwasrefinedusingsimulatedpatientsrecei
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