Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium.docVIP

Open Access Re 2009StableretVoal.lumesea10,rchIssue 9, Article R102 Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium Richard A Stabler*, Miao He?, Lisa Dawson*, Melissa Martin*, Esmeralda Valiente*, Craig Corton?, Trevor D Lawley?, Mohammed Sebaihia?, Michael A Quail?, Graham Rose?, Dale N Gerding?, Maryse Gibert§, Michel R Popoff§, Julian Parkhill?, Gordon Dougan? and Brendan W Wren* Addresses: *London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK. ?Wellcome Tru