Correlation of CAG repeat length between the maternal and paternal allele of the Huntingtin gene evidence for assortative mating.docVIP

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Correlation of CAG repeat length between the maternal and paternal allele of the Huntingtin gene evidence for assortative mating.doc

Correlation of CAG repeat length between the maternal and paternal allele of the Huntingtin gene evidence for assortative mating

Nopoulosetal.BehavioralandBrainFunctions2011,7:45 /content/7/1/45 SHORT PAPER OpenAccess CorrelationofCAGrepeatlengthbetweenthe maternalandpaternalalleleoftheHuntingtin gene:evidenceforassortativemating PegNopoulos1,2,3*,EricAEpping1,TomWassink1,BradleyLSchlaggar4,5,6,7 andJoelPerlmutter4,6,7,8 Abstract Tripletrepeatscontributetonormalvariationinbehavioraltraitsandwhenexpanded,causebraindisorders.While Huntington’sDiseaseisknowntobecausedbyaCAGtripletrepeatinthegeneHuntingtin,theeffectofCAG repeatsonbrainfunctionbelowdiseasethresholdhasnotbeenstudied.Thecurrentstudyshowsasignificant cor

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Correlation of CAG repeat length between the maternal and paternal allele of the Huntingtin gene evidence for assortative mating.docVIP