Effects of unilateral decompressive craniectomy on patients with unilateral acute post-traumatic brain swelling after severe traumatic brain injury.docVIP

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Effects of unilateral decompressive craniectomy on patients with unilateral acute post-traumatic brain swelling after severe traumatic brain injury.doc

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Effects of unilateral decompressive craniectomy on patients with unilateral acute post-traumatic brain swelling after severe traumatic brain injury

Available online /content/13/6/R185 Research Open Access Vol 13 No 6 Effects of unilateral decompressive craniectomy on patients with unilateral acute post-traumatic brain swelling after severe traumatic brain injury Wusi Qiu1,2,3*, Chenchen Guo1,2, Hong Shen2,3*, Keyong Chen1, Liang Wen2, Hongjie Huang1, Min Ding1, Li Sun1, Qizhou Jiang1 and Weiming Wang1 1Department of Neurosurgery, Hangzhou Second Hospital, College of Medicine, Hangzhou Normal University, 126 Wenzhou Road, Hangzhou, 310015, China 2Brain Medicine Research Institute, College of Medicine, Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, China 3Department of Neurosurgery, Second Affiliated Hospital, College of Medicine, Zhejiang University, 88 Jiefang Road, Hangzhou, 310009, China * Contributed equally Corresponding author: Hong Shen, sh_2nd@163.com Received: 6 Apr 2009 Revisions requested: 3 Jun 2009 Revisions received: 21 Aug 2009 Accepted: 23 Nov 2009 Published: 23 Nov 2009 Critical Care 2009, 13:R185 (doi:10.1186/cc8178) This article is online at: /content/13/6/R185 ? 2009 Qiu et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/ 2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction Acute post-traumatic brain swelling (BS) is one of the pathological forms that need emergent treatment following traumatic brain injury. There is controversy about the effects of craniotomy on acute post-traumatic BS. The aim of the present 13.518 +/- 2.33 mmHg versus 19.95 +/- 2.24 mmHg, 18.32 +/ - 1.77 mmHg, 21.05 +/- 2.23 mmHg and 17.68 +/- 1.40 mmHg, respectively). The mortality rates at 1 month after treatment were 27% in the unilateral DC group and 57% in the control group (p = 0.010). Good neurological outcome (GOS Score of 4 to 5) rates 1 year after injury for the groups were 56.8% and 32.4%,