Epidemiologic heterogeneity of common mood and anxiety disorders over the lifecourse in the general population a systematic review.docVIP

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Epidemiologic heterogeneity of common mood and anxiety disorders over the lifecourse in the general population a systematic review.doc

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Epidemiologic heterogeneity of common mood and anxiety disorders over the lifecourse in the general population a systematic review

BMC Psychiatry BioMedCentral Research article Open Access Epidemiologic heterogeneity of common mood and anxiety disorders over the lifecourse in the general population: a systematic review Arijit Nandi1, John R Beard2,3,4 and Sandro Galea*2,5,6,7 Address: 1Center for Population and Development Studies, Harvard School of Public Health, Boston, USA, 2Center for Urban Epidemiologic Studies, New York Academy of Medicine, New York, USA, 3School of Public Health, University of Sydney, Sydney, Australia, 4Faculty of Health and Applied Science, Southern Cross University, Lismore, Australia, 5Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, USA, 6Department of Epidemiology, Columbia University Mailman School of Public Health, New York, USA and 7Survey Research Center, Institute for Social Research, Ann Arbor, USA Email: Arijit Nandi - anandi@; John R Beard - jbeard@; Sandro Galea* - sgalea@ * Corresponding author Published: 1 June 2009 Received: 11 November 2008 Accepted: 1 June 2009 BMC Psychiatry 2009, 9:31 doi:10.1186/1471-244X-9-31 This article is available from: /1471-244X/9/31 ? 2009 Nandi et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Clinical evidence has long suggested there may be heterogeneity in the patterns and predictors of common mood and anxiety disorders; however, epidemiologic studies have generally treated these outcomes as homogenous entities. The objective of this study was to systematically review the epidemiologic evidence for potential patterns of heterogeneity of common mood and anxiety disorders over the lifecourse in the general population. Methods: We reviewed epidemiologic studies examining heterogeneity in either the natu