门冬氨酸鸟氨酸针持续微量泵给药对肝性脑病患者肝功能及血氨水平的影响.pdfVIP

实用临床医药杂志 • 110 • Journal of Clinic在1 Medicine in Practice 2013 年第 17 卷第7 期 门冬氨酸鸟氨酸针持续微量泵给药对肝性脑病患者 肝功能及血氨水平的影晌 黄献球 (广西壮族自治区桂东人民医院肝科，广西梧州， 54300 1) 摘 要:目的 探讨门冬氨酸鸟氨酸针持续微量泵注入治疗肝性脑病的临床疗效。方法 将 71 例肝性脑病患者随机分 为治疗组(n = 36)和对照组(η=36) ，治疗组应用门冬氨酸鸟氨酸针微量泵注入，对照组应用门冬氨酸鸟氨酸针静脉滴注。观 察2 组患者神志恢复正常时间及治疗前后肝功能、血氨值变化情况。结果 治疗组患者苏醒时间为(11.2 士 2. 1) h，对照组苏 醒时间为(18.S :l: 2.3) h，治疗组患者苏醒时间明显短于对照组。 2 组治疗后血氨、丙氨酸氨基转移酶(ALT) 、总胆红素 (四IL)均较治疗前明显降低治疗组治疗后血氨、ALT、TBIL 水平明显低于对照组治疗后。结论 应用门冬氨酸鸟氨酸针持 续微量泵注入比单纯静脉滴注疗效更佳，值得临床推广应用。 关键词:肝性脑病;门冬氨酸鸟氨酸;微量泵 中图分类号: R 742 文献标志码:A 文章编号: 1672-2353(2013)07-110-02 以)1: 10. 7619 Íjcrnp. 201307039 Effects of sustained micro - pump injection of ornithine aspartate needle on liver function and blood ammonia for patients with hepatic encephalopathy HUANG Xianqiu (Gu他η~g Peoρ，fes Hospiω! ， Wu劝ou ， Guangxi , 54300 1) ABS 1RACf: Objective To explore the clinical effects of sustained micro- pump injection of omithine aspartate needle in the treatment of hepatic encephalopathy. Methods Seventy 一 one pa- tients with hepatic encephalopathy were randomly divided into treatment group (η= 36) and ∞n­ trol group (η= 35). The treatment group was administered micro - p山np injection of omithine as- P盯tate needle while the control group applied intravenous drip of omithine aspartate needle. Both groups , in te口ns of conscious recovery time and changes of liver function and bl∞d 缸nmonia before and after treatment , were observed. Results Patients revival time of the treatment group (11.2 士 2. l) hw.出 significantly shorter than that of the control group (1 8.5 :t 2.3) h. After treatment , bl∞d am