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Neuroscience Research 64 (2009) 41–49 Contents lists available at ScienceDirect Neuroscience Research journal h omepage: www.els /locat e/neures Characterisation of human mesenchymal stem cells following differentiation into Schwann cell-like cells Maria Brohlin a,1, Daljeet Mahay b,1, Lev N. Novikov a, Giorgio Terenghi b, Mikael Wiberg a,c, Susan G. Shawcross b, Liudmila N. Novikova a,* a ˚ ˚ Department of Integrative Medical Biology, Section of Anatomy, Umea University, SE-901 87 Umea, Sweden b Blond McIndoe Research Laboratories, Tissue Injury and Repair Group, The University of Manchester, 3.106 Stopford Building, Oxford Road, Manchester M13 9PT, UK c ˚ ˚ Department of Surgical and Perioperative Science, Section of Hand and Plastic Surgery, Umea University, SE-901 87 Umea, Sweden A R T I C L E I N F O A B S T R A C T Article history: Cell-based therapies provide a clinically applicable and available alternative to nerve autografts. Our Received 7 October 2008 previous studies have characterised rat-derived mesenchymal stem cells (MSC) and here we have Received in revised form 7 January 2009 investigated the phenotypic, molecular and functional characteristics of human-derived MSC (hMSC) Accepted 16 January 2009 differentiated along a Schwann cell lineage. The hMS