小儿造血与血象特色(国外英文资料).docVIP

小儿造血与血象特点 The characteristic of hematopoiesis and hematopoiesis The hematopoietic organ originated from the middle of the embryo, and the main organs of hematopoiesis are not the same in the different stages of development of the embryo and the period after birth. One, the characteristic of haematopoiesis (1) the formation of hematopoietic hematopoietic blood cells of the fetus begins from the blood island of the yolk sac, and then the hematopoiesis of the liver and spleen is then transferred to the bone marrow for blood. Fetal hematopoiesis can be divided into three stages: 1. The mesoderm hematopoietic period Since embryos formed on 3 ~ 4 weeks in yolk sac many blood island, the island of blood cells, is divided into internal and external two copies of cells to form on the edge of the vascular network of original endothelial cells, cells from the blood vessels in the middle of the free to the lumen, into a primitive cells, staining shows strong basophilia, excluding hemoglobin, began to appear after differentiation of eggs as raw red blood cells, blood volume is larger, the cells nuclear chromatin coarse, similar to the gigantic young cell. After eight weeks, the island began to deteriorate. The blood cells of the megaloblast were gradually reduced to 12 to 15 weeks. The stage of hematopoiesis in the liver and spleen. At the beginning of the eighth week of the embryo, hematopoietic cells appear in the sinus gap in the liver. Liver manufacture of red blood cells and the yolk sac of the original red blood cell, the cell body is small, and the structure of the nucleus and marrow of approximate the original red blood cells, known as the shape of the original red blood cells, which can differentiate into seedless red blood cells, blood sinus wall into the bloodstream. Embryo 2-6 months, the liver blood is the most active, visible at this time a small amount of platelets and granulocyte, about 3 months in fetal spleen produces red blood cells, neutrophils and monocytes