高内涵药物筛选方法研究及应用.pdfVIP

# 486# A c ta Pharm aceut ca S n ca 2005, 40 ( 6) : 486- 490 张 莉, 杜冠华* ( , 100050) : ; ; : R 965. 1 : A : 05 13- 4 870( 2005) 06- 0486- 05 H igh content drug screening and its application * ZHANG L , DU Guan-hu a ( Institute of M ateriaM ed ica, ChineseA cademy of M ed ical S ciences and P eking UnionM edical College, B eij ing 1000 0, China) K ey words: h gh content screen ng; drug d scovery; ce ll-based assay ( h gh-throughput screen ng, HTS) 20 80 , , , 199 8 , , [ 1, 2 ] , , ) ) ) , ( h gh-content screen ng, HCS ) , , [ 3] 10 1 ( u ltra h gh-throughput screen ng, U ltra-HTS) , , , , , , 20 , 1997 , , , , , : 2004-08-18. [ 4- 6] : ( 30 17 1148 ) ; ( 02-03Z P08