抗菌药物临床应用原则(国外英文资料).docVIP

抗菌药物临床应用原则(国外英文资料) First, the indications and cautions of common antimicrobial drugs I penicillin class antibiotic The drugs can be divided into: (1) drugs such as penicillin (G), phenoxymethylpenicillin, etc. (2) penicillin-resistant penicillin, such as methoxylin, benzazole, cloazole, etc. (3), a broad-spectrum penicillin for part of e. coli with antibacterial activity such as ampicillin, amoxicillin, for most of gram-negative bacillus include verdigris false bacterium antibacterial activity, such as piperacillin, mezlocillin, etc. Indications: 1. Penicillin: suitable for hemolytic streptococcus, streptococcus pneumoniae, s. aureus bacteria that are sensitive to penicillin and gram positive bacteria infections, including sepsis, pneumonia, meningitis, respiratory infections, otitis media, and tetanus, gas gangrene, anthrax, diphtheria, meningitis, syphilis, gonorrhea, relapsing fever, leptospirosis, actinomycosis, etc. Procaine penicillin is available for muscle injection, benzathine penicillin for long-term preparation, phenylmethoxypenicillin acid can be taken orally, and its antibacterial spectrum is similar to penicillin. : resistance to penicillin enzyme penicillin antibacterial spectrum similar to penicillin, effect is a bit poor, but the stability of penicillin enzyme, can be used for enzyme production of penicillin resistant staphylococcus aureus infection. Broad-spectrum penicillin: similar to penicillin of gram positive bacteria, to gram-negative bacteria effectively, at the same time can also be used for the intestinal, urinary, biliary tract, abdominal cavity infection, etc. 2. The matters needing attention (1) no matter which way you give the medicine, you must ask for the history of penicillin allergy and other allergy history before you use it, and you must make a skin test first. (2) once penicillin anaphylactic shock is taken, the injection of adrenalin, oxygen, and corticosteroids is administered. (3) the whole body can be applied to large doses