诺和锐30roadshow2012v3format.pptVIP

* While overall use of multiple OAD therapy and/or insulin has often been found to be associated with poor glycaemic control, Simons et al. found an association between immediate or rapid transition to the use of insulin and improved HbA1c control over time and a reduction in the risk of micro- and macrovascular complications by 27%, as compared to other treatment strategies, including stepwise OAD treatment. The study also reported a direct correlation between the increasing number of treatment intensification steps and a greater risk of complications. These findings suggest that, in general,