Human herpesvirus 4(国外英文资料).docVIP

Human herpesvirus 4(国外英文资料) EB virus (EBv Human herpes virus Human herpesvirus 4 (hhv-4) ) In the United States of China????????? EB virus (EBv Human herpes virus Human herpesvirus 4 (hhv-4) ) A summary of the EB virus: ????? Epstein Barr Virus (EBv), also known as Human herpesvirus 4 (hhv-4). Is a scientist and Epstein Barr two people for the first time in 1964 to childrens African burkitt lymphoma cells successfully built by suspension culture in vitro, and plant cells smear under construction using electron microscope to herpes virus particles, so the name. Two, morphological characteristics: Epsteins form is similar to other herpes viruses, round and 180nm in diameter, with a basic structure containing nucleoid, capsid and cystic membrane. The nucleoid is a dense object with a diameter of 45nm in diameter, which contains two strands of linear DNA, the length of which varies with different strains and the average is 17.5 by 104 bp molecular weight 108. The capsid is a 20-sided stereoscopic symmetry consisting of 162 shells of shells. The capsule consists of a nuclear membrane of an infected cell, which has the viral encoding of the membrane glycoprotein, the Epstein receptor on the lymphocyte, and the fusion of the cell. In addition, there is a layer of protein between the capsule and the capsid. Iii. Derived diseases: The EB virus can only be found in B lymphocytes The multiplication of the medium can make it grow Issue of the wedding. Cells infected by the virus The genome of EBv can be produced All kinds of antigen: EBv (EBna) Early antigen (ea) Membrane antigen (ma) Capsid antigen (vca) Lymphocyte recognition membrane antigen???????????????????????????????????????????????????? [lydma) ????? The five antigens in patients with nasopharyngeal cancer: 1 EBna 2 ma 3 vca 4 ea 5 lydma Except for the first 5 lydma antigen, The corresponding lgG and lgA are generated Antibody, study these antigens and their Antibody, to clarify EBv and nasopharyngeal Bo