DIC的诊断标准(国外英文资料).docVIP

DIC的诊断标准(国外英文资料) DIC diagnostic criteria In October 1999, the 7th national blood clot and hemostasis symposium proposed the following diagnostic criteria. Clinical diagnosis is the basic disease of D IC, such as infection, malignant tumor, pathology, major surgery and trauma. There are two other clinical manifestations: (1) severe or multiple bleeding; (2) the microcirculation disorder or shock that cannot be explained by the original pathogenesis; (3) extensive skin, mucosal embolism, focal ischemic necrosis, shedding and ulceration, or the failure of organs such as lungs, kidneys, and brains of unknown causes; (4) anticoagulation therapy is effective. 2, the experimental diagnosis (1) general abnormal experimental diagnosis at the same time, more than any of the following three cases: (1) PLT progressive decline in 100 x 109 / L (liver disease, leukemia 50 x 109 / L), or more than two platelet activation molecular markers of plasma levels: beta TG, PF4, thrombus alkanes B2 (TXB2), P - select element. Plasma Fg content 1.5 g/L (liver Disease 1.0 g/L, leukemia 1.8 g/L) or 4.0 g/L, or progressive reduction. The 3P test positive, or the plasma FDP 20 mg/L ( 60mg/L) or plasma d-d levels were more than four times higher than normal (positive). The PT extended or shortened the 3s (the liver disease 5s), and APTT extended or shortened 10s. (5) the AT - Ⅲ: A 60% () does not apply to liver disease or lower protein C (PC) activity. The plasma fibrinolysin antigen (PLG: Ag) 200mg/L. Ⅷ 7 factors: activity C 50% (necessary) liver disease. The plasma endothelial - 1 (ET - 1) level 80 pg/ml or coagulase regulating protein (TM) was more than twice as high as normal. (2) the experimental diagnosis of difficult cases should be as follows: 1, 1, 1, 2, TAT and FPA; The level of SFMC increased; The level of PAP increases; The level of TFPI (TFPI) was reduced by the level of the TF (positive) and the tissue factor pathway (TFPI). (3) leukemia DIC laboratory diagnostic crite