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肺动脉高压(PAH)专家共叫(国外英文资料)
肺动脉高压(PAH)专家共识(国外英文资料)
Pulmonary hypertension (PAH) expert consensus
Publisher: qin dawn (visit: 822)
ACCF/AHA promulgated the consensus of experts on pulmonary hypertension (PAH) and published in J? Am? Coll? Cardiol. The main points are as follows:?
1? Pahs are a form of pulmonary vascular resistance (PVR), which is limited by blood flow to the pulmonary artery, which eventually leads to the syndrome of right ventricular failure. Various pathophysiological pathways make pulmonary vessel smooth muscle, endothelial cells and outer membrane reshaped and cause vasoconstrictor imbalance. The heart of the central hospital in the city of xianyang
2? The most common type of PAH (IPAH) is women. Familial PAH is associated with the osteoprotein receptor -2, which is the autosomal incomplete dominant hereditary disease; PAH with congenital heart disease, connective tissue disease, drugs and toxins, human immunodeficiency virus (HIV), portal hypertension, hemoglobin disease and bone marrow hyperplastic diseases. The incidence of congenital heart disease was 8 cases per thousand live births, and 30 percent of those who had not been treated developed pahs.
3? At current levels of treatment, pahs have a mortality rate of about 15 percent. A predictor of poor prognosis include: high function classification, poor sports ability, right atrial pressure, severe right ventricular dysfunction, cardiac index is low, increasing brain natriuretic peptide, etc.
4? There is a high risk of pahs in the following situations and should be checked regularly, the family history of the IPAH, the series of diseases of scleroderma, the high pressure of the portal vein after transplantation. Echocardiography is an effective screening method for screening suspicious PAH.
5? The right cardiac catheterization is a clear diagnosis of pahs. PAH hemodynamics is defined as the average pulmonary artery pressure of > 25 mmHg, pulmonary capillaries (PCW), left room pressure, or left ventricular diastolic pres
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